Loading...
Market
Will Cassava Sciences present detailed Simufilam trial results at a major medical meeting by mid-2025?
2
Resolution / Starting Odds
Yes • 50%
No • 50%
Announcements from Cassava Sciences or coverage of major medical conferences
Story
Cassava's Simufilam Fails Phase 3 Alzheimer's Trial; Company Discontinues Trials, Shares Plunge 85%
Nov 25, 2024, 12:55 PM
Cassava Sciences announced that its Alzheimer's drug, Simufilam, failed to meet co-primary, secondary, and exploratory endpoints in the Phase 3 ReThink-ALZ trial. The study showed that Simufilam did not demonstrate a significant reduction in cognitive or functional decline versus placebo in patients with mild-to-moderate Alzheimer's disease. Despite Simufilam demonstrating an overall favorable safety profile, the company plans to discontinue the second Phase 3 ReFocus-ALZ trial and the Open Label Extension study. Following the announcement, trading of Cassava Sciences' stock was halted, and the stock price dropped by over 85% pre-market. The company plans to present detailed results at a future medical meeting.
View original story
Similar markets
New Alzheimer's drug candidate announced • 25%
Focus shifts to different therapeutic area • 25%
Company gets acquired • 25%
Continues current operations without major changes • 25%
Favorable ruling for Cassava Sciences • 25%
Unfavorable ruling for Cassava Sciences • 25%
Settlement • 25%
Case dismissed • 25%
Successful with measurable cognitive improvement • 25%
Partially successful with some cognitive improvement • 25%
Unsuccessful with no cognitive improvement • 25%
Trial canceled or postponed • 25%
Yes • 50%
No • 50%
Yes • 50%
No • 50%
