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Will Cassava Sciences secure a new partnership or funding by mid-2025?
3
Resolution / Starting Odds
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Official announcements from Cassava Sciences or reputable financial news sources
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Cassava's Simufilam Fails ReThink-ALZ Phase 3 Trial; Shares Plunge 80%
Nov 25, 2024, 12:35 PM
Cassava Sciences announced on November 25th that its Phase 3 ReThink-ALZ trial of simufilam, a treatment for mild-to-moderate Alzheimer's disease, failed to meet co-primary endpoints. The drug did not show a significant reduction in cognitive or functional decline versus placebo. Consequently, the company plans to discontinue the second Phase 3 ReFocus-ALZ trial and the Open Label Extension study. Shares of Cassava Sciences fell over 80% following the announcement. The company stated that simufilam continued to demonstrate an overall favorable safety profile and has $149 million in cash reserves.
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