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Will Novo Nordisk announce a new weight loss target for CagriSema by the end of 2025?
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Yes • 50%
No • 50%
Official press releases from Novo Nordisk
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Novo Nordisk Shares Plunge 29% After CagriSema Falls Short of 25% Weight Loss Target
Dec 20, 2024, 12:30 PM
Novo Nordisk announced that its experimental obesity drug CagriSema achieved a 22.7% weight loss in adults with obesity or overweight in the REDEFINE 1 Phase 3 trial after 68 weeks. While this result demonstrated superior weight loss compared to semaglutide 2.4 mg (16.1%), cagrilintide 2.4 mg (11.8%), and placebo (2.3%), it fell short of the company's anticipated target of 25% weight loss. Following the announcement, Novo Nordisk's shares plunged as much as 29%, marking the largest single-day drop on record for the company and erasing over $140 billion in market value.
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Similar markets
Seek further trials • 25%
Submit for regulatory approval • 25%
Discontinue development • 25%
Partner with another company • 25%
Yes • 50%
No • 50%
New drug entering Phase 3 trials • 25%
Improved results for CagriSema • 25%
Partnership with another company • 25%
No major announcement • 25%
Exceeds expectations • 25%
Meets expectations • 25%
Falls short of expectations • 25%
Trial cancelled • 25%
Yes • 50%
No • 50%
