Study Shows Anti-IL-11 Drug Extends Lifespan of Mice by 25%, Reduces Cancer and Gray Hair

Jul 17, 2024, 04:25 PM

A recent study published in Nature has shown that inhibiting interleukin-11 (IL-11), a pro-inflammatory cytokine, can significantly extend the lifespan of mice. The research demonstrated that both genetic deletion and pharmacological inhibition of IL-11 increased the lifespan of laboratory mice by nearly 25%. The treated mice, referred to as 'supermodel grannies' due to their youthful appearance, were healthier, stronger, and exhibited fewer age-related health problems. The study found that male mice experienced a 22.5% increase in median lifespan. Additionally, the treatment reduced the incidence of cancer and gray hair. Anti-IL-11 therapies are already in human clinical trials, raising hopes for their potential application in extending human lifespan and improving healthspan.