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VisitRegeneron Milestone Payment to Mammoth by End of 2024
Yes • 50%
No • 50%
Financial disclosures from Regeneron or Mammoth Biosciences
Regeneron Invests $100M in CRISPR Therapies with Mammoth Biosciences
Apr 25, 2024, 01:45 PM
Regeneron Pharmaceuticals has expanded its presence in the field of gene editing by entering into a significant partnership with Mammoth Biosciences, a Brisbane, CA-based biotech company co-founded by CRISPR pioneer Jennifer Doudna. The collaboration focuses on developing in vivo CRISPR-based gene editing therapies aimed at multiple tissues and cell types. Regeneron will make an upfront payment and equity investment totaling $100 million, along with additional milestone payments. This deal is part of Regeneron's broader strategy to enhance its genetic medicine portfolio, which includes other initiatives like a longstanding research agreement with Intellia Therapeutics targeting the rare disease transthyretin amyloidosis and the acquisition of a gene therapy biotech.
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Profitable • 25%
Break-even • 25%
Minor losses • 25%
Significant losses • 25%
Discovery of a new CRISPR enzyme • 33%
Successful editing of a complex genetic condition in vitro • 33%
Patenting a novel delivery mechanism • 34%
1-2 diseases • 33%
3-4 diseases • 33%
5 or more diseases • 33%
Yes, for one therapy • 40%
No • 40%
Yes, for more than one therapy • 20%
Sickle Cell Disease • 25%
Transthyretin Amyloidosis • 25%
Cystic Fibrosis • 25%
Muscular Dystrophy • 25%