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VisitFirst Human Trials of Regeneron-Mammoth CRISPR Therapy by 2025
Yes • 50%
No • 50%
Press releases from Regeneron or Mammoth Biosciences, clinical trial registries
Regeneron Invests $100M in CRISPR Therapies with Mammoth Biosciences
Apr 25, 2024, 01:45 PM
Regeneron Pharmaceuticals has expanded its presence in the field of gene editing by entering into a significant partnership with Mammoth Biosciences, a Brisbane, CA-based biotech company co-founded by CRISPR pioneer Jennifer Doudna. The collaboration focuses on developing in vivo CRISPR-based gene editing therapies aimed at multiple tissues and cell types. Regeneron will make an upfront payment and equity investment totaling $100 million, along with additional milestone payments. This deal is part of Regeneron's broader strategy to enhance its genetic medicine portfolio, which includes other initiatives like a longstanding research agreement with Intellia Therapeutics targeting the rare disease transthyretin amyloidosis and the acquisition of a gene therapy biotech.
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In Vivo Therapy • 33%
Ex Vivo Therapy • 33%
Diagnostic Tool • 34%
Cancer • 20%
Rare genetic disorders • 20%
Heart disease • 20%
Neurological disorders • 20%
Other • 20%
Cancer • 25%
Rare Genetic Disorders • 25%
Heart Disease • 25%
Neurodegenerative Diseases • 25%
Below 25% • 25%
25% to 50% • 25%
51% to 75% • 25%
Above 75% • 25%
Yes, for one therapy • 40%
No • 40%
Yes, for more than one therapy • 20%
Sickle Cell Disease • 25%
Transthyretin Amyloidosis • 25%
Cystic Fibrosis • 25%
Muscular Dystrophy • 25%