Loading...
Market
First crop species genetically modified using bridge RNA-guided DNA recombination by end of 2024?
5
Resolution / Starting Odds
Corn • 25%
Soybean • 25%
Rice • 25%
Wheat • 25%
Peer-reviewed journals indexed in PubMed or official announcements from agricultural research institutions
Story
Arc Institute's Bridge RNA-Guided DNA Recombination Published in Nature for Precise Genome Editing
Jun 26, 2024, 04:20 PM
Researchers from the Arc Institute have introduced a groundbreaking genome engineering technology known as bridge RNA-guided DNA recombination. This new mechanism, detailed in two papers published in Nature, allows for the programmable insertion, excision, or inversion of DNA sequences. Unlike CRISPR, bridge RNA-guided DNA recombination does not rely on cellular repair mechanisms, potentially making it safer and more precise. The discovery includes three atomic structures of the first natural RNA-guided recombinase, which enhances the power and precision of genome editing for long DNA sequences. This modular system involves the IS110 recombinase and non-coding RNA, significantly reshaping animal and plant genomes.
View original story
Similar markets
Yes • 50%
No • 50%
Corn • 25%
Wheat • 25%
Rice • 25%
Other • 25%
Gene therapy • 33%
Agricultural biotechnology • 33%
Synthetic biology • 33%
Nestle • 25%
Kraft Heinz • 25%
Unilever • 25%
Other • 25%
FDA (US) • 25%
EMA (Europe) • 25%
NMPA (China) • 25%
Other • 25%
Approved • 25%
Pending • 25%
Rejected • 25%
Withdrawn • 25%
Successfully completed • 25%
Partially successful • 25%
Unsuccessful • 25%
Not completed • 25%