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Market
Will Zepbound be prescribed to over 1 million patients for sleep apnea by 2024?
3
Resolution / Starting Odds
Yes • 50%
No • 50%
Prescription data from healthcare providers and industry reports
Story
FDA Approves Eli Lilly's Weight-Loss Drug Zepbound as First Treatment for Obstructive Sleep Apnea
Dec 20, 2024, 10:17 PM
The U.S. Food and Drug Administration (FDA) has approved Eli Lilly's weight-loss drug Zepbound (tirzepatide) as the first and only prescription medication for the treatment of moderate-to-severe obstructive sleep apnea in adults with obesity. This approval allows the drug to be used in combination with a reduced-calorie diet and increased physical activity. Clinical studies have shown that patients treated with Zepbound experienced a mean reduction of 63% in the apnea-hypopnea index (AHI), equating to about 30 fewer breathing interruptions per hour, and up to 50% of patients had no symptoms after one year. The approval opens the door for broader insurance coverage of the medication, marking a significant advancement in the management of obstructive sleep apnea, a condition affecting approximately 39 million adults in the United States.
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Yes • 50%
No • 50%
Improves blood pressure only • 33%
Improves blood pressure and one other measure • 33%
Improves blood pressure and multiple other measures • 33%
Less than 100,000 • 25%
100,000 to 200,000 • 25%
200,001 to 300,000 • 25%
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10% to 20% • 25%
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≥ 50% • 50%
< 50% • 50%
Approved without conditions • 33%
Approved with conditions • 33%
Not approved • 33%
No additional studies • 33%
1-2 additional studies • 33%
3 or more additional studies • 33%