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FDA Approves Rybrevant for Second-Line EGFR-Mutated Lung Cancer, Reducing Progression Risk by Over 50%
Sep 20, 2024, 05:47 AM
Rybrevant (amivantamab-vmjw), in combination with standard of care chemotherapy, has been approved in the U.S. as the first and only targeted regimen for second-line treatment of EGFR-mutated advanced lung cancer. The approval by the FDA is expected to significantly reduce the risk of disease progression by more than 50%. This marks the third new indication for Johnson & Johnson in 2024. The pharmaceutical giant has set a target of $5 billion in sales for Rybrevant, following this approval for EGFR-positive non-small cell lung cancer (NSCLC) with EGFR ex19del/L858R substitution mutations.
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