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Will Merck's immunotherapy show a median overall survival of 75 months in the next trial results by end of 2024?
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Resolution / Starting Odds
Yes • 50%
No • 50%
Merck's clinical trial publications and announcements
Story
CheckMate 067: Decade of Immunotherapy Advances Boosts Advanced Melanoma Survival to 72 Months
Sep 16, 2024, 12:30 PM
A decade of advancements in immunotherapy has significantly improved survival rates for patients with advanced melanoma. The CheckMate 067 trial revealed that the combination of nivolumab and ipilimumab resulted in a median overall survival of 72 months, compared to 37 months with nivolumab alone and 20 months with ipilimumab alone. The trial results were presented at the European Society for Medical Oncology (ESMO) 2024 conference. Merck presented 10-year follow-up data for their immunotherapy, highlighting the long-term benefits in metastatic melanoma survival. The medical community, including Weill Cornell, acknowledges the progress but emphasizes that further work is needed. The double drug treatment raises survival rate for half of advanced melanoma to 10 years.
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Yes • 50%
No • 50%
Yes • 50%
No • 50%
PFS < 6 months • 25%
PFS 6-8 months • 25%
PFS 8-10 months • 25%
PFS > 10 months • 25%
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No • 50%
Positive - Significant survival improvement • 25%
Neutral - No significant difference • 25%
Negative - Worse outcomes • 25%
Trial inconclusive • 25%
Significant Improvement • 33%
No Change • 33%
Significant Adverse Effects • 34%
Yes • 50%
No • 50%
