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Will Genentech's RGT-4198 CDK inhibitor progress to Phase 2 clinical trials by September 30, 2025?
2
Resolution / Starting Odds
Yes • 50%
No • 50%
Clinical trial registries and Genentech's official announcements
Story
Genentech Acquires Regor's CDK Inhibitors in Definitive Purchase Agreement for $850M
Sep 30, 2024, 11:05 AM
Genentech has announced the acquisition of Regor's portfolio of next-generation CDK inhibitors for $850 million upfront, with potential additional milestone payments. This acquisition includes CDK inhibitors such as RGT-4198, which is in phase 1 and targets CDK4/2/6 with some CDK9 activity. The deal is part of a Definitive Purchase Agreement and is expected to enhance Genentech's oncology pipeline, particularly in the treatment of breast cancer. Roche, the parent company of Genentech, is also projecting more than 3 billion Swiss francs ($3.6 billion) in peak sales from its drug candidates in obesity and diabetes, acquired from Carmot Therapeutics.
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Yes • 50%
No • 50%
Yes • 50%
No • 50%
Yes • 50%
No • 50%
Breast cancer • 25%
Lung cancer • 25%
Colorectal cancer • 25%
Other cancer types • 25%
Increase by more than 10% • 25%
Increase by 5-10% • 25%
Increase by less than 5% • 25%
Decrease or no change • 25%
Positive results • 25%
Negative results • 25%
Inconclusive results • 25%
Trial extended • 25%
Positive results • 25%
Negative results • 25%
Mixed results • 25%
No results announced • 25%
