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Will a reprogrammed astroglia-based therapy for brain circuit restoration succeed in human trials by end of 2025?
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Official announcements from clinical trial registries or peer-reviewed publications
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Reprogrammed Brain Cells Could Restore Damaged Circuits, Specific Interneurons
Nov 11, 2024, 04:15 PM
Researchers have successfully reprogrammed brain support cells called astroglia into neuron-like cells that mimic specific interneurons vital for brain functions. This study, focusing on regenerative medicine, could potentially restore damaged brain circuits. Additionally, new research shows that astrocytes, non-neuronal brain cells, help determine whether memories are stored long-term or forgotten. In mice, acidifying astrocytes shortly after a traumatic event led to the memory fading within a short period.
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