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Will a major pharmaceutical company partner with Stanford on PAGER-based therapies by end of 2025?
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Official announcements from Stanford or the pharmaceutical company
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Stanford Develops PAGERs for Programmable Cell Behavior Control
Dec 5, 2024, 09:22 AM
Researchers from Stanford University have developed a new technology involving synthetic G protein-coupled receptors (GPCRs) known as programmable antigen-gated G-protein-coupled engineered receptors (PAGERs). These PAGERs can sense diverse antigens and trigger a range of intracellular responses, acting as logic gates for programmable expression. This technology allows for the detection of both soluble and cell-attached antigens, potentially leading to advancements in cell behavior control with applications in immunotherapy and synthetic biology.
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