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What will be the key milestone achieved by Jnana Therapeutics under Otsuka's ownership by December 31, 2024?
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Resolution / Starting Odds
FDA approval of JNT-517 • 25%
Initiation of Phase 3 trials for JNT-517 • 25%
New drug discovery announcement • 25%
Other • 25%
Official press releases from Jnana Therapeutics or Otsuka Pharmaceutical, financial news outlets like Bloomberg or Reuters
Story
Otsuka Pharmaceutical to Acquire Boston-based Jnana Therapeutics for Up to $1.1 Billion
Aug 1, 2024, 05:26 AM
Japan's Otsuka Pharmaceutical announced on Thursday that it will acquire U.S.-based Jnana Therapeutics for up to $1.1 billion. The deal includes an upfront payment of $800 million and potential milestone payments of up to $325 million. Jnana Therapeutics, based in Boston, is known for its RAPID platform and the investigational drug JNT-517, which has shown effectiveness in treating phenylketonuria (PKU) in Phase 1b/2 trials. Following the acquisition, Jnana will operate as a subsidiary of Otsuka in Boston, continuing its research and development efforts. PKU is a rare inherited metabolic disorder characterized by high levels of phenylalanine in the blood. Jnana's CEO and co-founder is Joanne Kotz, and the company is also involved in research related to autoimmune diseases.
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Autoimmune diseases • 25%
Neurological disorders • 25%
Metabolic disorders • 25%
Other therapeutic areas • 25%
Joanne Kotz remains CEO • 25%
New CEO appointed from Otsuka • 25%
New CEO appointed externally • 25%
Other leadership changes • 25%
None • 25%
Up to $100M • 25%
$100M to $200M • 25%
Over $200M • 25%
Preclinical success • 25%
Phase 1 completion • 25%
Phase 2 completion • 25%
Phase 3 initiation • 25%
Positive results • 25%
Negative results • 25%
Mixed results • 25%
No results announced • 25%
Phase II trial completion • 25%
Phase III trial commencement • 25%
FDA approval • 25%
None of the above • 25%
Start of Phase 3 trial • 33%
FDA approval • 33%
Partnership announcement • 33%
Successful with no major adverse effects • 25%
Successful with minor adverse effects • 25%
Unsuccessful due to lack of efficacy • 25%
Unsuccessful due to major adverse effects • 25%
Positive • 25%
Negative • 25%
Neutral • 25%
Not Reported • 25%