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What extent of mobility improvement will DBS achieve in paraplegic patients by end of 2025?
2
Resolution / Starting Odds
No improvement • 25%
Partial improvement (e.g., short distances) • 25%
Significant improvement (e.g., walking long distances) • 25%
Full mobility restoration • 25%
Study results published in peer-reviewed journals
Story
Swiss Researchers Restore Walking in Paraplegic Patients with Brain Stimulation Targeting Lateral Hypothalamus
Dec 2, 2024, 05:15 PM
Swiss researchers have achieved a groundbreaking medical advancement by enabling two paraplegic patients with partial spinal cord injuries to walk again using deep brain stimulation (DBS). The technique involves implanting electrodes in the lateral hypothalamus, a brain region not traditionally associated with movement, to stimulate neural activity. This innovative approach has shown promising results, allowing the patients to walk short distances, climb stairs, and improve lower limb movements. The study, published in Nature Medicine, also demonstrated similar recovery outcomes in preclinical models, including mice and rats. These findings highlight the potential of DBS as a transformative therapy for spinal cord injury rehabilitation.
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Full mobility restoration in a patient • 25%
Widespread clinical trials • 25%
FDA approval • 25%
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Mayo Clinic • 25%
Johns Hopkins Hospital • 25%
Cleveland Clinic • 25%
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