Syracuse upset No. 25 UNLV 44-41 in an overtime thriller at Allegiant Stadium in Las Vegas, handing the Rebels their first loss of the season. The game featured a controversial roughing-the-passer penalty against UNLV that extended Syracuse's game-tying drive in regulation. Quarterback Kyle McCord led the Orange with 377 total yards and three touchdowns. Running back LeQuint Allen was instrumental, scoring four touchdowns, including the game-winner in overtime. Syracuse overcame a 10-point deficit in the third quarter and tied the game with 23 seconds remaining. This victory marks Syracuse's first road win against a ranked team since 2010 and their second win against an AP-ranked team in the regular season for the first time since 2001.