Swiss Researchers Use Hypothalamus Stimulation and Implants to Restore Walking in Paralysed Patients

Dec 2, 2024, 07:03 PM

Swiss researchers have achieved a breakthrough in spinal cord injury rehabilitation by using deep brain stimulation (DBS) targeting the lateral hypothalamus. The study, published in Nature Medicine and conducted by researchers from EPFL and Lausanne University Hospital, enabled two partially paralysed patients to regain the ability to walk short distances and climb stairs. This pioneering technique, involving electrode implants, activates residual neural connections, promoting recovery of lower limb movements. The findings were validated in preclinical models involving mice and rats, as well as in a first-in-human feasibility study. The research highlights the potential of DBS as a transformative therapy for spinal cord injuries.