Japanese Researchers Test Drug to Regrow Third Set of Teeth, Targeting USAG-1 Protein in Clinical Trials

Dec 13, 2024, 01:30 PM

Japanese researchers are conducting clinical trials on a pioneering drug designed to stimulate the growth of a third set of teeth, which could provide a natural alternative to dentures and implants. The drug targets the USAG-1 protein and utilizes RNA technology to promote tooth regeneration. This development is significant as it challenges the long-held belief that humans and most mammals only grow two sets of teeth. Additionally, a study has identified 18 genomic regions linked to tooth shape and size, including a gene inherited from Neanderthals that influences these characteristics. The research is led by Katsu Takahashi at a medical research facility in Japan.