First CAR-T Cell Therapy for 15-Year-Old with Lupus in Germany Shows Promising Results

Jul 11, 2024, 02:36 PM

The world's first CAR-T cell therapy for a child with lupus has shown promising results. A 15-year-old teen from Universitätsklinikum Erlangen in Germany received the treatment in 2023 and reported feeling as good as before the diagnosis, with only a few colds. Previously, CAR-T cells had been used primarily for leukemia, lymphoma, and in studies on adults with advanced autoimmune diseases. This marks the first time the therapy has been used for treating children with autoimmune conditions. The findings were published in a new paper in The Lancet. The breakthrough was highlighted by NatureBiotech and acknowledged by BertrandBio.