Dark Microglia's Toxic Lipids Linked to Alzheimer's, Offering Potential Therapy

Dec 24, 2024, 07:47 PM

Researchers have identified a new mechanism involving 'dark microglia', a subset of brain immune cells, that may contribute to Alzheimer's disease. This discovery suggests that dark microglia produce and release toxic lipids, which can damage neurons. The study, published in the journal Neuron, indicates that inhibiting this mechanism in mice prevents neurodegeneration. The findings point to potential therapeutic targets for slowing down or even reversing Alzheimer's disease, according to the researchers involved.