Chiefs Beat 49ers 28-18, Mahomes Now 5-0 Against San Francisco

Oct 20, 2024, 11:13 PM

The Kansas City Chiefs defeated the San Francisco 49ers 28-18, achieving their highest point total of the season and maintaining their undefeated record at 6-0 as the NFL's only unbeaten team. Patrick Mahomes, now 11-3 as an underdog in his career, improved his all-time record against the 49ers to 5-0. Despite being intercepted twice and held to under 160 passing yards, Mahomes led the Chiefs to victory, highlighted by a significant scramble at the end of the third quarter. Andy Reid's teams are now 22-4 after a bye week in the regular season. The 49ers, whose special teams struggled, dropped to 3-4 and fell out of first place in the NFC West. This loss marks the biggest regular-season defeat for the 49ers since Week 7 of the previous year, when they also lost to the Chiefs 44-23.