US Patent and Trademark Office records

Study: cNST in Brain Regulates Immune System, ColumbiaMed Research Shows

May 2, 2024, 09:47 AM

Recent research has uncovered a significant link between the brain and immune system regulation. Scientists, including HHMI Investigator Charles Zuker and colleagues from ColumbiaMed and ZuckermanBrain, have identified a specific brain region that communicates with the body's immune system through vagal neurons. This interaction, involving the cNST, can either enhance or suppress inflammation. The study, detailed in Nature, utilized advanced techniques such as single-cell sequencing, functional imaging, and spatial omics to map out a new neural circuit in the brain. This discovery not only advances our understanding of the body-brain axis but also highlights potential new avenues for treating inflammatory diseases.